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Advances in metabolic biotransformation and its applications.

Lianxu Manz

The biotransformation field is constantly evolving with the discovery of new molecular structures and metabolic pathways that impact efficacy and safety. Scientists in the fields of biotransformation and mechanistic drug metabolism are critical to advancing chemicals through discovery and development, but the number of academically trained scientists for this role is declining. This position paper highlights the continued demand for biotransformation scientists and the need to educate them and encourage creative ways to ensure future growth in the field.