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Analysis of mean platelet volume in chronic obstructive pulmonary disease patients during acute attack

Mehmet Zahid Ko

Aims: We aimed to study the association between mean platelet volume (MPV), a marker of platelet activation and inflammation, in patients with Chronic Obstructive Pulmonary Disease (COPD) during acute attack.

Methods: Forty patients with acute exacerbation of COPD and another forty subjects in stable period of COPD were included to the study. White blood cell count, hemoglobin, hematocrit, platelet and MPV values of the study groups analyzed. Results: MPV of the COPD patients with acute exacerbation was significantly higher than the control group (p<0.001).

Conclusion: MPV increases during acute exacerbation of COPD. Due to its simplicity and inexpensive nature, it can be used as a complementary inflammatory marker of acute attack.