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Balancing Excitation and Inhibition: Inhibitory Postsynaptic Potentials in the Brain

Jack Michael

 An inhibitory postsynaptic potential (IPSP) is a type of electrical potential change that occurs in the postsynaptic neuron in response to the release of neurotransmitters by the presynaptic neuron. IPSPs result in a hyperpolarization of the postsynaptic neuron, making it less likely to fire an action potential and reducing its excitability.