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Bone marrow-derived cells in haematogenous tumour metastasis: emerging targets for therapy

Madame Spyri*

Hematogenous tumor metastasis, the spread of cancer cells via the bloodstream, is a major cause of mortality in cancer patients. Recent studies have identified bone marrow-derived cells as key players in this process, contributing to the formation of pre-metastatic niches and facilitating the survival and growth of metastatic tumor cells. In this perspective, we will discuss the emerging role of bone marrow-derived cells in hematogenous tumor metastasis and the potential for these cells to serve as targets for therapeutic intervention.