Абстрактный
Comprehensive Clinical Evaluations of the Aesthetic Enhancements on Skin, Hair, and Nails through the Administration of Marine Collagen
Maheshwari Patel, Samrat Warma, Himanshi Warma,Apeksha Merja, Nayan Patel
Collagen is abundant, forming 70-80% of skin's dry weight in mammals. Studies highlight improved skin, hair, and nail conditions post collagen treatment. We aimed to assess the safety, tolerability and effectiveness of AQUACOLTM, a marine collagen derived from fish skin by proprietary process (enzyme hydrolysis), across various dosages (2.5g, 5g and 10g) in adult human participants. The study included 66 male and female participants, aged 30 to 50, who had mild to moderate wrinkles (crows' feet) around the eyes and experienced joint discomfort, swelling, stiffness, and limited motion. The study also included individuals concerned about hair loss, reduced hair growth, and brittle nails. AQUACOLTM usage led to statistical significant (p-value<0.0001) results with clinically significant improvement with 61.90% reduction in crow's feet wrinkles, 22.94% enhanced skin hydration, 16.52% higher hair density, 25.68% increased hair thickness, decreased pain by 47.32%, 15.45% improved skin elasticity, 39% (p-value<0.005) smoother skin, 53.72% (p-value<0.001) less hair fall and upper body muscle strength rose by 82.64%. Assessments showed significant improvements in sleep quality. All subjects perceived the product, highly effective and beneficial for skin, hair, nails and muscles strength. No subjects experienced serious adverse events or product-related adverse event. The study's findings indicated that a 2.5g dose improved skin health and elasticity, while a 10g dose alleviated joint pain and enhanced muscle strength. These results, supported by both measurements and participant input, emphasize AQUACOLTM's potential as a safe, well-tolerated, and effective contributor to overall physical well-being, particularly in the aspects of skin, hair, and nail quality