Журнал клинической патологии и лабораторной медицины


Current knowledge regarding: diagnosis and treatment of Alzheimer's disease

Lee Chang-Min

The most prevalent cause of dementia in the world is Alzheimer's disease, and as the global population ages, its incidence is only increasing. The two signature diseases of this neurodegenerative disease process are the accumulation of amyloid plaques and neurofibrillary tangles of hyper phosphorylated tau. The clinical presentation must meet a number of criteria for a diagnosis, and fluid and imaging indicators are also considered. Although there are trials underway to lessen the generation and overall load of disease inside the brain, treatment is primarily focused on symptomatic treatments. Here, we review recent developments in our knowledge of the clinical diagnosis and management of Alzheimer's disease and provide updates on ongoing clinical trials.