Абстрактный

Difference of thyroid hormone reference ranges in diagnosis of thyroid functions between normal pregnant women in the early, middle and late pregnancy and normal adults

Qian Fang, Wang Jun, Lv Honglei

Objective: To discuss and analyze the difference in thyroid hormone reference ranges between normal pregnant women and normal adults, and study the thyroid dysfunction in pregnant women during pregnancy.

Methods: Blood samples of 166 pregnant women and 50 non-pregnant women were randomly collected, to detect Thyroid Stimulating Hormone (TSH), Free Triiodothyronine (FT3), Free Thyroxine (FT4), Total Triiodothyronine (TT3) and Total Thyroxine (TT4).

Results: The ratio of thyroid dysfunction was 9.64% (16/166) by using normal thyroid hormone reference ranges of pregnant women as an index, while the ratio of thyroid dysfunction was 1.20% (2/166) by using the normal thyroid hormone reference ranges of non-pregnant women as an index. The difference in thyroid hormone reference ranges between the two methods was statistically significant (P<0.05).

Conclusions: There were significant differences in thyroid hormone levels between pregnant women and non-pregnant women, and between women during different stages of pregnancy, and the ratio of thyroid dysfunction during pregnancy was 9.64%; therefore, thyroid function screening is necessary in all pregnant women.