Абстрактный

Drug binding receptors to the envelope glycoprotein in viral structures.

Gary Clark

Virus–receptor intuitive play a key administrative part in viral have extend, tissue tropism, and viral pathogenesis. Infections utilize exquisite techniques to join to one or numerous receptors, overcome the plasma film obstruction, enter, and get to the essential have cell apparatus. The viral connection protein can be seen as the “key” that opens have cells by association with the “lock”—the receptor—on the cell surface, and these lock-and-key intelligent are basic for infections to effectively attack have cells. Numerous common topics have developed in virus–receptor utilization inside and over infection families illustrating that infections regularly target specific classes of particles in arrange to intercede these occasions. Common viral receptors incorporate sialylated glycans, cell grip particles such as immunoglobulin superfamily individuals and integrins, and phosphatidylserine receptors.