Журнал клинической респираторной медицины

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Human Microbiome: An Exciting Opportunity to Develop Novel Treatments For Acne Vulgaris and Other Chronic Skin Diseases

Lada Rasochova

Acne is one of the most common skin diseases. It affects up to 85% of individuals worldwide, mainlyas adolescents, young adults and older women. There are four main factors that are thought to contribute to acne: Increased sebum production, follicular hyperkeratinization, colonization of follicles with Cutibacterium acnes and inflammation. Despite years of acne research, no novel products have been brought to market in the past 60 years and currently available treatments suffer from significant drawbacks: Lack of efficacy and side effects.