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Immunological Mechanisms of Cancer Immune Evasion and Strategies to Overcome Them

Perucae Perio

The immune system plays a crucial role in identifying and eliminating cancer cells from the body. However, cancer cells have developed various mechanisms to evade the immune system, leading to tumor progression and metastasis. Understanding these immunological mechanisms and developing strategies to overcome them is crucial for the development of effective cancer immunotherapies. This article will provide an overview of the immunological mechanisms used by cancer cells to evade the immune system, including alterations in antigen presentation, downregulation of immune checkpoint molecules, and recruitment of immunosuppressive cells. The article will also discuss the current immunotherapeutic approaches used to target these mechanisms, such as immune checkpoint inhibitors, adoptive T cell therapy, and cancer vaccines.