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Modulating peritoneal fibrinolysis as a therapeutic strategy for peritoneal fibrosis and adhesion formation

Chen Mengzi*

Peritoneal fibrosis and adhesion formation are common complications of abdominal surgery and peritoneal dialysis, and can result in significant morbidity and mortality. One potential therapeutic strategy is to modulate peritoneal fibrinolysis, the process by which fibrin clots are dissolved, to prevent the formation of fibrotic tissue and adhesions. In this commentary, we will discuss the potential benefits and limitations of modulating peritoneal fibrinolysis as a therapeutic strategy for peritoneal fibrosis and adhesion formation.