Журнал клинической патологии и лабораторной медицины

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Understanding the Mechanisms and Significance of Apoptosis

Edwin Agarwal

Apoptosis is a programmed cell death mechanism that plays a critical role in normal development, homeostasis, and the immune response. It involves a series of tightly regulated cellular events that ultimately lead to the dismantling and removal of the dying cell without triggering an inflammatory response. Apoptosis is essential for removing damaged or unwanted cells, such as those with DNA damage, viral infections, or cancerous mutations. Dysregulation of apoptosis has been implicated in numerous diseases, including cancer, autoimmune disorders, and neurodegenerative diseases. Understanding the molecular mechanisms underlying apoptosis has important implications for developing novel therapies for these diseases.