Журнал клинической патологии и лабораторной медицины


Whole blood immunoassay and biochemistry analysis on a fully integrated research department

Debra Donnelly

We describe a fully integrated system that can run sandwich-style immunoassays and numerous biochemical analyses simultaneously on a disc. Whole blood is directly transferred to a disposable "lab-on-a-disc" that also contains various freeze-dried reagents for blood chemistry analysis and immunoassay reagents. The complete process of plasma separation, metering, mixing, incubation, cleaning, and detection is fully automated thanks to the ground-breaking laser-irradiated Ferro wax micro valves and centrifugal microfluidics. To support the many types of reaction procedures, the analyser has an optical detection module that can measure absorbance at ten distinct wavelengths.